References

Carreira LM, Azevedo P. Comparison of the influence of CO2-laser and scalpel skin incisions on the surgical wound healing process. ARC Journal of Anesthesiology. 2016; 1:(3)1-8 https://doi.org/10.20431/2455-9792.0103001

Carstanjen B, Jordan P, Lepage OM. Carbon dioxide laser as a surgical instrument for sarcoid therapy–a retrospective study on 60 cases. Can Vet J. 1997; 38:773-776

Compston PC, Turner T, Wylie CE, Payne RJ. Laser surgery as a treatment for histologically confirmed sarcoids in the horse. Equine Vet J. 2016; 48:(4)451-456 https://doi.org/10.1111/evj.12456

Fretz PB, Barber SM. Prospective analysis of cryosurgery as the sole treatment for equine sarcoids. Vet Clin North Am Small Anim Pract. 1980; 10:(4)847-859 https://doi.org/10.1016/s0195-5616(80)50085-9

Hanson RR. Current Therapy In Equine Medicine.Philadelphia: W.B Saunders; 1997

Haspeslagh M, Vlaminck L, Martens A. The possible role of Stomoxyx calcitrans in equine sarcoid transmission. Vet J. 2018; 231:8-12 https://doi.org/10.1016/j.tvjl.2017.11.009

Hewes CA, Sullins KE. The use of cisplatin containing biodegradable beads for treatment of cutaneous neoplasia in Equidae: 59 cases (2000-2004). J Am Vet Med Assoc. 2006; 229:(10)1617-1622 https://doi.org/10.2460/javma.229.10.1617

Ireland JL, Wylie CE, Collins SN, Verheyen KLP, Newton JR. Preventive health care and owner-reported disease prevalence of horses and ponies in Great Britain. Res Vet Sci. 2013; 95:(2)418-424 https://doi.org/10.1016/j.rvsc.2013.05.007

Knottenbelt DC, Patterson-Kane JC, Snalune KL. Equine Clinical Oncology, 1st edn. : Elsevier; 2015

Knottenbelt DC. The Equine Sarcoid, Why are there so many treatment options?. Vet Clin North Am Equine Pract. 2019; 35:(2)243-262

Martens A, De Moor A, Demeulemeester J, Pellman L. Polymerase chain reaction analysis of the surgical margins of equine sarcoids for bovine Papilloma virus DNA. Vet Surg. 2001; 30:(5)460-467 https://doi.org/10.1053/jvet.2001.25874

McConahy FF, Davis RE, Reppas GP, Ralwinson RJ, McClintock SA, Hutchins DR, Hodgson DR. Management of equine sarcoids. New Zealand Vet J. 1994; 5:180-184 https://doi.org/10.1080/00480169.1994.35816

Platt JP, Simon BT, Coleman M, Martinez EA, Lepiz MA, Watts AE. The effects of multiple anaesthetic episodes on equine recovery quality. Equine Vet J. 2017; 50:(1)111-116 https://doi.org/10.1111/evj.12728

Smith AN, Klahn S, Philips B, Parshley L, Bennett P, Flory A, Calderon R. ACVIM small animal consensus statement on safe use of cytotoxic chemotherapeutics in veterinary practice. J Vet Intern Med. 2018; 32:(3)904-913

Taylor S, Haldorson G. A review of equine sarcoid. Equine Vet Educ. 2013; 25:(4)210-216 https://doi.org/10.1111/j.2042-3292.2012.00411.x

Tamzali Y, Borde L, Rols MP, Golizio M, Lyazrhi F, Teissie J. Successful treatment of equine sarcoids with cisplatin electrochemotherapy: A retrospective study of 48 cases. Equine Vet J. 2012; 44:214-220 https://doi.org/10.1111/j.2042-3306.2011.00425.x

Taylor SD, Toth B, Baseler L, Charney VA, Miller MA. Lack of correlation between Papillomaviral DNA in surgical margins and recurrence of equine sarcoids. J Equine Vet Sci. 2014; 34:(5)722-725 https://doi.org/10.1016/j.jevs.2013.12.012

Theon AP, Pascoe JR, Galuppo LD, Fisher PE, Griffey SM, Madigan JE. Comparison of perioperative intratumoural administration of cisplatin for treatment of cutaneous sarcoids and squamous cell carcinomas in horses. J Am Vet Med Assoc. 1999; 215:(11)1655-1660

Surgical management of sarcoids

02 September 2022
9 mins read
Volume 6 · Issue 5
Figure 1. Removal of a nodular sarcoid between the forelimbs, under standing sedation and local anaesthesia using a diode laser. The skin is placed under tension using Lane tissue forceps.
Figure 1. Removal of a nodular sarcoid between the forelimbs, under standing sedation and local anaesthesia using a diode laser. The skin is placed under tension using Lane tissue forceps.

Abstract

Equine sarcoids are the most common form of equine skin neoplasia, they can be challenging and expensive to treat. There are many different treatment options available to the equine clinician, with no one treatment suitable for all lesions in all locations. There is a lack of published evidence allowing direct comparison between different treatment within the literature. The use of laser surgery to remove sarcoids has become more popular in recent years and it provides a simple cost-effective way of managing many cases, with results similar to other treatments available. Histopathological analysis of any tissue removed is advisable, although the behaviour of sarcoids following removal is unpredictable and careful monitoring of the surgical site following any form of surgery is essential. If sarcoids recur following removal, then there are a variety of adjunctive therapies available to reduce the risk of further recurrence.

Equine sarcoids are the most common form of skin neoplasia in horses, with an owner reported frequency of 5.8% (Ireland et al, 2013). Bovine papillomavirus (BPV) types 1 and 2 are causally associated with the development and pathogenesis of equine sarcoids (Taylor and Haldorson, 2013). Sarcoids occur commonly in areas where biting flies congregate, including the medial aspects of the thighs, the ventral abdomen and axillae and around the eyes and ears. They can also occur on the distal limbs or trunk, particularly if there has been a previous wound. This has led to the speculation that the biting fly (Stomoxys calcitrans) may be a vector for transmission of disease. Research has shown that stable flies exposed to both equine sarcoid and bovine papilloma tissue resulted in a significant viral load within the fly, indicating that the flies may act as a vector for sarcoid transmission (Haspeslagh et al, 2018).

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